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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NT5DC1
All Species:
17.58
Human Site:
T407
Identified Species:
38.67
UniProt:
Q5TFE4
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TFE4
NP_689942.2
455
51845
T407
K
R
I
S
T
Y
S
T
I
A
I
P
S
I
E
Chimpanzee
Pan troglodytes
XP_518703
455
51825
T407
K
R
I
S
T
Y
S
T
I
A
I
P
S
I
E
Rhesus Macaque
Macaca mulatta
XP_001112048
455
51828
T407
K
R
I
S
T
Y
S
T
I
A
I
P
S
I
E
Dog
Lupus familis
XP_532271
471
53423
T423
K
R
I
S
T
Y
S
T
I
A
I
P
S
I
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5P5
467
53076
I417
S
T
Y
S
T
I
A
I
P
N
I
E
S
I
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507572
133
15081
N86
G
F
F
S
Q
I
P
N
Q
R
P
F
R
T
L
Chicken
Gallus gallus
XP_419778
454
52040
I406
C
I
S
T
Y
S
T
I
A
I
P
S
L
E
A
Frog
Xenopus laevis
Q6GN91
499
58768
T435
F
R
T
D
H
N
P
T
Y
F
L
R
R
L
S
Zebra Danio
Brachydanio rerio
NP_001098413
461
52643
S408
K
L
T
W
C
C
H
S
I
H
T
Y
S
T
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121742
508
59601
K461
P
A
I
P
L
T
I
K
E
Q
L
Q
Y
L
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001197549
242
27677
S195
G
Y
F
P
A
Y
K
S
D
P
L
K
Y
V
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.2
83
N.A.
78.5
N.A.
N.A.
24.1
75.1
21.4
62
N.A.
N.A.
25.7
N.A.
24.4
Protein Similarity:
100
100
99.1
87
N.A.
86
N.A.
N.A.
27.2
86.3
39.4
76.7
N.A.
N.A.
42.1
N.A.
34.5
P-Site Identity:
100
100
100
100
N.A.
33.3
N.A.
N.A.
6.6
0
13.3
20
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
40
N.A.
N.A.
6.6
13.3
26.6
26.6
N.A.
N.A.
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
0
10
0
10
37
0
0
0
0
19
% A
% Cys:
10
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
0
10
0
10
46
% E
% Phe:
10
10
19
0
0
0
0
0
0
10
0
10
0
0
0
% F
% Gly:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
10
0
0
10
0
0
0
0
0
% H
% Ile:
0
10
46
0
0
19
10
19
46
10
46
0
0
46
0
% I
% Lys:
46
0
0
0
0
0
10
10
0
0
0
10
0
0
0
% K
% Leu:
0
10
0
0
10
0
0
0
0
0
28
0
10
19
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
10
0
10
0
10
0
0
0
0
0
% N
% Pro:
10
0
0
19
0
0
19
0
10
10
19
37
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
10
10
0
10
0
0
0
% Q
% Arg:
0
46
0
0
0
0
0
0
0
10
0
10
19
0
0
% R
% Ser:
10
0
10
55
0
10
37
19
0
0
0
10
55
0
10
% S
% Thr:
0
10
19
10
46
10
10
46
0
0
10
0
0
19
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
10
0
10
46
0
0
10
0
0
10
19
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _